Manifest MedEx is California's largest nonprofit health information organization, serving as a pivotal health data utility for over 38 million residents across the state. The organization connects more than 3,000 healthcare entities, including hospitals, health plans, and medical groups, facilitating the secure exchange of real-time patient information. Manifest MedEx supports healthcare transformation and health equity by providing data solutions that enhance patient care, reduce costs, and improve outcomes. It acts as a Qualified Health Information Organization (QHIO) within the state's Data Exchange Framework, focusing on initiatives like population health management and meeting data sharing requirements.